common macrocarpium fruit
Liu Wei Di Huang Wan, also known as Liuwei Dihuang teapills (simplified Chinese: 六味地黄丸; traditional Chinese: 六味地黃丸; pinyin: liùwèi dìhuáng wán) or Six Flavor Rehmanni, is a prescription (方剂 fāng jì) in traditional Chinese medicine and pharmacy to treat yin deficiency. In Japanese kampo, it is known as “Rokumi-gan” (六味丸 ろくみがん) (it is also known as Kampo #87). It is commonly made into Chinese patent medicine.

== History ==
The formula was created by Qian Yi as dihuang pill (地黄丸). It was published in “Xiao’er Yao Zheng Zhi Jue” (also known as “Key to Therapeutics of Children’s Diseases” or “The Correct Execution of Pediatric Medicinals and Patterns” simplified Chinese: 小儿药证直诀; traditional Chinese: 小兒藥證直訣; pinyin: Xiǎo’ér Yào Zhèng Zhí Jué) in 1119 by Qian Yi’s student.The formula was altered slightly when it was borrowed as a Japanese kampo formula. Some Chinese species of herbs were replaced with herbs found in Japan. For example, Alisma plantago-aquatica was replaced with Alisma orientale for zé xiè.

== Derivatives ==
The Liuwei Dihuang Wan is one of the most important Chinese
patent medicines, and is widely used in eastern Asia. In China, there are hundreds of medicinal manufacturers who produce Liuwei
Dihuang Wan and its derivatives. These derivatives include Zhibai Dihuang Wan, Guifu Dihuang Wan, Mingmu Dihuang Wan, Qiju Dihuang
Wan, Maiwei Dihuang Wan, and Guishao Dihuang Wan.

We share with you a blind Chinese medicine – dogwood
Be
【Overview of traditional Chinese medicine of Cornus officinalis】
It is the mature pulp of Cornus officinalis, a small tree plant of the Cornus family. Acid, lukewarm. Return to the liver and kidney meridians.
1. Kidney-tonifying astringent essence: used for kidney deficiency, impotence, nocturnal emission, soreness and coldness of waist and knees, aversion to cold, frequent urination, etc. Dan).
2. Tonic for Liver and Kidney: It is used for uterine bleeding due to deficiency of liver and kidney, deficiency of Chong and Ren, and heavy menstrual flow, such as (Liuwei Dihuang Wan).
3. Astringing sweat and fixing off: It is used for profuse sweating, if the body is weak and wants to lose it, it has the effect of collecting sweat and fixing off. It can be used with ginseng, keel, etc. for traditional Chinese medicine practitioners.
【Pharmaceutical identification of Cornus officinalis】
Cornus officinalis and Shudi can nourish the liver and kidney. However, Shudi is better than Yijing and blood, and its power is better than that of dogwood, but it does not help Yang, and it does not have astringent properties. This product can not only tonify yin, but also yang, so it is an essential medicine for nourishing liver and kidney (yin and yang).
【Pharmacological effects of Cornus officinalis】
1. Has the effect of lowering blood pressure;
2. Has the effect of inhibiting intestinal spasm;
3. Has the effect of inhibiting Staphylococcus aureus and Shigella;
4. It can improve the decrease of white blood cells caused by radiotherapy and chemotherapy.
[Chemical composition of Cornus]
Contains gallic acid, malic acid, tartaric acid, cornus glycosides and vitamin A substances.
【Dosage and usage of dogwood】
3——10g, simmer in water.
【Notes】
The core of dogwood is not used for medicinal purposes, so it should be removed so that the weight is sufficient (avoid filling the core with meat).

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